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Based upon this finding, the investigatorsrecommend 500ml of irrigation every 15 min during extensive spine surgery [32].Retrospective reports have suggested that topical application of vancomycin powderintraoperatively prior to closure of the incision reduces SSI after spine surgery, thoughthis result should be confirmed in well-designed trials prior to widespread adoption[8, 33]

Based upon this finding, the investigatorsrecommend 500ml of irrigation every 15 min during extensive spine surgery [32].Retrospective reports have suggested that topical application of vancomycin powderintraoperatively prior to closure of the incision reduces SSI after spine surgery, thoughthis result should be confirmed in well-designed trials prior to widespread adoption[8, 33]. These granules are different from thecytotoxic granules that contain the 9kDa form of granulysin because they are devoid ofperforin and GrB and as mentioned above, are released during the cell‘s activation phase andnot during effector-target contact

These granules are different from thecytotoxic granules that contain the 9kDa form of granulysin because they are devoid ofperforin and GrB and as mentioned above, are released during the cell‘s activation phase andnot during effector-target contact.

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The converseis also true, and there are degrees of supportdepending upon the amount of force generated bythe patient’s respiratory muscles.